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Peptide record

TPDB62356

FAM-GYR Blood-Brain Barrier Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB62356
FAM-GYR
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict Peptipedia CPPsite3.0
standard
No
A 15-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Chemical: NanoLigand Carriers (NLCs) , nanofibres N-terminal: Addition of Cysteine
Sequence
GYRPVHNIRGHWAPG
Physicochemical Analysis
C78H113N27O18
DCEQLKMFST
G
1716.93
11.16
4
0
5
+2
1.69
-1.000
52.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
407.12
2
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
3
G
2
H
1
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 2 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
15
C78H113N27O18
1716.93
11.16
+2
1.69
-1.000
Free
NanoLigand Carriers (NLCs) , nanofibres
L
Amphiphilic
Linear
Addition of Cysteine
N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@H]1CC(=O)OOC(=O)[C@H]2N(C1=O)CCC2
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

hCMEC/D3 Cells, MCF-7 Cells , Ebm-2 And MCF-10A Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Protein derived
5-FAM at N terminal
Low cellular uptake than FAM-CGY
In vitro
CGGGTTTTSSCC
Additional Detail Fields 1 fields
CGGGTTTTSSCC