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Peptide record

TPDB62347

YM-3 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB62347
YM-3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with nanoparticle
Sequence
GYGRKKRRGRRRTHRLPRRRRRR
Physicochemical Analysis
C126H232N66O26
ANDCEQIMFSWV
R
3087.65
13.14
16
0
2
+15
12.59
-3.065
16.96
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
48.26
2
Residue Composition
number
0
A
13
R
0
N
0
D
0
C
0
E
0
Q
3
G
1
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 13 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
23
C126H232N66O26
3087.65
13.14
+15
12.59
-3.065
Conjugation with nanoparticle
L
Linear
Free
NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 20100203611

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nanoparticle
Cytoplasm and nucleus
In vitro
CCGGGCCCSCSSSCCCTTCCCC
Additional Detail Fields 1 fields
CCGGGCCCSCSSSCCCTTCCCC