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Peptide record

TPDB62346

No. 440 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB62346
No. 440
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, and Peptipedia, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
GYGNCRHFKQKPRRD
Physicochemical Analysis
C79H124N30O21S1
AEILMSTWV
R
1862.10
10.70
6
1
2
+4
5.76
-2.227
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
80.02
4
Residue Composition
number
0
A
3
R
1
N
1
D
1
C
0
E
1
Q
2
G
1
H
0
I
0
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 1 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 0 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
15
C79H124N30O21S1
1862.10
10.70
+4
5.76
-2.227
Free
L
Amphipathic
Linear
Conjugation with fluorescein
NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, Jurkat and CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Similar or greater than TAT in CHO cells
In vitro
CCTTSSSSSSCSCC
Additional Detail Fields 1 fields
CCTTSSSSSSCSCC