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Peptide record

TPDB62345

ZF5.3 Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB62345
ZF5.3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GWYSCNVCGKAFVLSRHLNRHLRVHRRATAS
Physicochemical Analysis
C156H248N56O39S2
DEQIMP
R
3596.16
11.83
9
0
12
+6
2.93
-0.384
75.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7115
197.85
9
Residue Composition
number
3
A
5
R
2
N
0
D
2
C
0
E
0
Q
2
G
3
H
0
I
3
L
1
K
0
M
1
F
0
P
3
S
1
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 5 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 3 I: 0 L: 3 K: 1 M: 0 F: 1 P: 0 S: 3 T: 1 W: 1 Y: 1 V: 3
Chemical Descriptors
31
C156H248N56O39S2
3596.16
11.83
+6
2.93
-0.384
Free
L
Cationic
Linear
Free
NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
GFP-HiBiT fusion protein
Cytosol
Significantly enhanced delivery (7- to 30-fold increase)
Endocytosis
In vitro
CCBTTTBCCCC
Additional Detail Fields 1 fields
CCBTTTBCCCC