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Peptide record

TPDB62343

TP11 Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB62343
TP11
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation at amino group of Lys
Sequence
GWTLNSKINLKALAALAKKIL
Physicochemical Analysis
C106H184N28O26
RDCEQHMFPYV
L
2266.80
11.00
4
0
12
+4
-0.87
0.467
149.05
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
242.63
4
Residue Composition
number
4
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
5
L
4
K
0
M
0
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 5 K: 4 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C106H184N28O26
2266.80
11.00
+4
-0.87
0.467
Free
L
Amphipathic
Linear
Biotinylation at amino group of Lys
NCC(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human bowes melanoma cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Biotin
Cytoplasm and nucleus and intracellular membranous structures
Lower than Transportan
Non-receptor mediated endocytosis
In vitro
CCCTTCCCCHHHHHHHTTTCC
Additional Detail Fields 1 fields
CCCTTCCCCHHHHHHHTTTCC