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Peptide record

TPDB62342

TP9 Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB62342
TP9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation at amino group of Lys
Sequence
GWTLNSAGYLLGKLKALAALAKKIL
Physicochemical Analysis
C124H209N31O30
RDCEQHMFPV
L
2614.21
10.64
4
0
15
+4
-3.19
0.644
144.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
267.38
4
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
7
L
4
K
0
M
0
F
0
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 7 K: 4 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
25
C124H209N31O30
2614.21
10.64
+4
-3.19
0.644
Free
L
Amphipathic
Linear
Biotinylation at amino group of Lys
NCC(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human bowes melanoma cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Biotin
Cytoplasm and nucleus and intracellular membranous structures
Comparable to Transportan
Non-receptor mediated endocytosis
In vitro
CCSSCCCIIIIIHHHHHHHHHTTCC
Additional Detail Fields 1 fields
CCSSCCCIIIIIHHHHHHHHHTTCC