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Peptide record

TPDB62339

Transportan Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62339
Transportan
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GWTLNSAGYLLGKINLKALAALAKKL
Physicochemical Analysis
C128H215N33O32
RDCEQHMFPV
L
2728.32
10.64
4
0
15
+4
-2.77
0.485
139.23
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
256.20
5
Residue Composition
number
5
A
0
R
2
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
7
L
4
K
0
M
0
F
0
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 7 K: 4 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
26
C128H215N33O32
2728.32
10.64
+4
-2.77
0.485
Free
L
Amphiphilic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, A549,Caco-2, THP-1, and RAW264.7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Protein derived
Salmonella phage selz
Late Endosomes/Lysosomes
selzTransportan showed a significantly higher (P < 0.05) uptake number of phages than WT selz in A549 cells and P < 0.01 in HeLa cells.
In vitro
CCCCCCC
Additional Detail Fields 1 fields
CCCCCCC