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Peptide record

TPDB62330

MAAPC02 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62330
MAAPC02
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GWIRNQFRKIWQR
Physicochemical Analysis
C83H126N28O17
ADCEHLMPSTYV
R
1788.09
12.71
4
0
5
+4
-0.44
-1.408
60.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
615.18
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
2
Q
1
G
0
H
2
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 2 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C83H126N28O17
1788.09
12.71
+4
-0.44
-1.408
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli D31 And E. Coli Ml35 And Hrbcs

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
aminoglycoside tobramycin at N terminal
Displayed relatively low OM permeabilization at MICs (20 μM).
In vitro
CTTCCCCCCCCC
Additional Detail Fields 1 fields
CTTCCCCCCCCC