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Peptide record

TPDB62325

EGFP-LMWP Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62325
EGFP-LMWP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
N-terminal: Conjugated with EGFP
Sequence
GSVSRRRRRRGGRRRR
Physicochemical Analysis
C77H150N46O19
ANDCEQHILKMFPTWY
R
2024.33
13.35
10
0
1
+10
8.46
-2.725
18.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C77H150N46O19
2024.33
13.35
+10
8.46
-2.725
Free
L
Cationic
Linear
Conjugated with EGFP
NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mouse macrophage-like cell line J774 A.5

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Protein (eGFP)
Cytoplasm and nucleus
Showed increased uptake efficiency
In vitro
CCCCTTCSSCCCCCCC
Additional Detail Fields 1 fields
CCCCTTCSSCCCCCCC