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Peptide record

TPDB62318

Pep1-E1A-EL Cell-penetrating Peptides standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB62318
Pep1-E1A-EL
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 49-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FLAG epitope
Sequence
GSHMKETWWETWWTEWSQPKKKRKVLEEPGQPLDELCKRPRDYKDDDDK
Physicochemical Analysis
C273H409N75O82S2
ANIF
K
6117.82
5.66
12
12
11
-1
22.20
-1.910
29.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
28990
473.86
9
Residue Composition
number
0
A
3
R
0
N
6
D
1
C
6
E
2
Q
2
G
1
H
0
I
3
L
8
K
1
M
0
F
4
P
2
S
3
T
5
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 6 C: 1 E: 6 Q: 2 G: 2 H: 1 I: 0 L: 3 K: 8 M: 1 F: 0 P: 4 S: 2 T: 3 W: 5 Y: 1 V: 1
Chemical Descriptors
49
C273H409N75O82S2
6117.82
5.66
-1
22.20
-1.910
Conjugated with FLAG epitope
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

H1299, A375, B16-F0

Assay & Model

C57BL/6 male mice (16–17 weeks and 30–35 g)
C57BL/6 male mice (16–17 weeks and 30–35 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
E1A peptides and FITC‐labeled
Nucleus
In vitro and in vivo
CCCTTTHHHHHHHHHHGGGGHHHHGGGCCC
Additional Detail Fields 1 fields
CCCTTTHHHHHHHHHHGGGGHHHHGGGCCC