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Peptide record

TPDB62317

TAT-E1A-EL Cell-penetrating Peptides standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB62317
TAT-E1A-EL
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 41-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FLAG epitope
Sequence
GSHMGRKKRRQRRRPPQLEEPGQPLDLSCKRPRDYKDDDDK
Physicochemical Analysis
C205H343N75O64S2
ANIFTWV
R
4946.56
10.45
14
8
5
+5
25.00
-2.280
28.54
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
30.12
7
Residue Composition
number
0
A
8
R
0
N
6
D
1
C
2
E
3
Q
3
G
1
H
0
I
3
L
5
K
1
M
0
F
5
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 6 C: 1 E: 2 Q: 3 G: 3 H: 1 I: 0 L: 3 K: 5 M: 1 F: 0 P: 5 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
41
C205H343N75O64S2
4946.56
10.45
+5
25.00
-2.280
Conjugated with FLAG epitope
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

H1299, A375, B16-F0

Assay & Model

C57BL/6 male mice (16–17 weeks and 30–35 g)
C57BL/6 male mice (16–17 weeks and 30–35 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
E1A peptides and FITC‐labeled
Nucleus
In vitro and in vivo
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCSSSTTCCCTTTTC