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Peptide record

TPDB62314

R8-azido-peptide Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB62314
R8-azido-peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: P-Azidophenylalanine At N Terminus
Sequence
GSGSGGRRRRRRRR
Physicochemical Analysis
C62H120N38O17
ANDCEQHILKMFPTWYV
R
1669.88
13.25
8
0
0
+8
6.78
-2.800
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C62H120N38O17
1669.88
13.25
+8
6.78
-2.800
Free
L
Cationic
Linear
P-Azidophenylalanine At N Terminus
NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Te671(Loxp-Lacz) And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Cre recombinase
Cytoplasm and nucleus
The maximum LacZ expression level reached to 22.7% for R8-Ca-cMSN
In vitro
CCSTTSCCCCCCCC
Additional Detail Fields 1 fields
CCSTTSCCCCCCCC