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Peptide record

TPDB62312

(42-38)-(9-1) Crot Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB62312
(42-38)-(9-1) Crot
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with rhodamine B
Sequence
GSGKKGGKKHCQKY
Physicochemical Analysis
C64H108N22O18S1
ARNDEILMFPTWV
K
1505.76
10.48
6
0
1
+5
5.48
-1.957
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
98.95
4
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
1
Q
4
G
1
H
0
I
0
L
5
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 4 H: 1 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C64H108N22O18S1
1505.76
10.48
+5
5.48
-1.957
Free
L
Linear
Conjugation with rhodamine B
NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (rhodamine)
Probably nucleus and nucleolus
Receptor mediated endocytosis
In vitro
CGGGTCTTCCTTC
Additional Detail Fields 1 fields
CGGGTCTTCCTTC