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Peptide record

TPDB62310

SFTI-M6 SFTI-M7 Cell-penetrating Peptides modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB62310
SFTI-M6 SFTI-M7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 14-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: X, α-aminobutyric acid N-terminal: Conjugation with Alexa Flour 488
Sequence
GRXTKSIPPIXFPD
Physicochemical Analysis
C61H98N16O17
ANCEQHLMWYV
P
1327.55
10.09
2
1
3
+1
2.91
-0.486
55.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
2
I
0
L
1
K
0
M
1
F
3
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 0 K: 1 M: 0 F: 1 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C61H98N16O17
1327.55
10.09
+1
2.91
-0.486
Free
X, α-aminobutyric acid
Modified
Cyclic
Conjugation with Alexa Flour 488
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Cyclic Modified
Synthetic
Fluorophore (Alexa Fluor 488)
Equal to SFTI-1
Non-receptor and non-specific endocytosis dependent mechanism
In vitro
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Cyclic Modified
Synthetic
Fluorophore (Alexa Fluor 488)
Equal to SFTI-1
Non-receptor and non-specific endocytosis dependent mechanism
In vitro