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Peptide record

TPDB62302

HEN1/NSLC1 Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB62302
HEN1/NSLC1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
GRRRRATAKYRTAH
Physicochemical Analysis
C70H122N32O18
NDCEQILMFPSWV
R
1699.94
12.58
7
0
4
+6
4.84
-1.950
21.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
87.65
3
Residue Composition
number
3
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C70H122N32O18
1699.94
12.58
+6
4.84
-1.950
Free
L
Cationic
Linear
Biotinylation
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO or HEK 293T cells

Source & Reference

CPPsite3.0
CPPsite3
US 7754678

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
Nucleus
In vitro
CCCCCCSSSCCCC
Additional Detail Fields 1 fields
CCCCCCSSSCCCC