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Peptide record

TPDB62265

RB3 Cell-penetrating Peptides standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB62265
RB3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 41-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-GRKKRRQRRRPPCVPYLGMYLTDLVFIEEGTPNYTEDGLVN-NH2
Physicochemical Analysis
C213H342N64O61S2
AHSW
R
4839.57
9.83
8
5
13
+3
12.28
-0.910
68.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4470
92.36
10
Residue Composition
number
0
A
6
R
2
N
2
D
1
C
3
E
1
Q
4
G
0
H
1
I
4
L
2
K
1
M
1
F
4
P
0
S
3
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 2 D: 2 C: 1 E: 3 Q: 1 G: 4 H: 0 I: 1 L: 4 K: 2 M: 1 F: 1 P: 4 S: 0 T: 3 W: 0 Y: 3 V: 3
Chemical Descriptors
41
C213H342N64O61S2
4839.57
9.83
+3
12.28
-0.910
Amidation
L
Linear
Acetylation
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Acute Brain Slices Of Mice

Assay & Model

Male C57Bl/6 mice
Male C57Bl/6 mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vivo and ex vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC