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Peptide record

TPDB62253

TAT_SpyT Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB62253
TAT_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GRKKRRQRRRGASAHIVMVDAYKPTKG
Physicochemical Analysis
C132H232N52O34S1
NCELFW
R
3123.68
12.42
11
1
8
+9
10.49
-1.415
47.04
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
47.70
4
Residue Composition
number
3
A
6
R
0
N
1
D
0
C
0
E
1
Q
3
G
1
H
1
I
0
L
4
K
1
M
0
F
1
P
1
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 0 K: 4 M: 1 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
27
C132H232N52O34S1
3123.68
12.42
+9
10.49
-1.415
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Endosomes
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC