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Peptide record

TPDB62231

PPC5 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62231
PPC5
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GRKAARAPGRRKQ
Physicochemical Analysis
C59H110N28O15
NDCEHILMFSTWYV
R
1451.70
12.88
6
0
3
+6
5.76
-2.023
23.08
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
3
A
4
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C59H110N28O15
1451.70
12.88
+6
5.76
-2.023
Free
L
Linear
Free
N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PMO and Cy5.5 dye
Increased fluorescence by more than 3-fold
Macropinocytosis
In vitro
CCSTTTBCSSCBCC
Additional Detail Fields 1 fields
CCSTTTBCSSCBCC