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Peptide record

TPDB62229

Pep2 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62229
Pep2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Chemical: Phosphorylation N-terminal: Acetylation
Sequence
Ac-GRGDSPRRSPRR
Physicochemical Analysis
C54H97N27O17
ANCEQHILKMFTWYV
R
1396.54
12.58
5
1
0
+4
6.46
-2.633
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
5
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C54H97N27O17
1396.54
12.58
+4
6.46
-2.633
Free
Phosphorylation
L
Cationic
Linear
Acetylation
NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa and A549

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nucleic acid (Plasmid DNA)
Cytoplasm and nucleus
Low comapred tp PEP4
In vitro
CCCCCTTTSSCC
Additional Detail Fields 1 fields
CCCCCTTTSSCC