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Peptide record

TPDB62215

aPP6R1 Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB62215
aPP6R1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GPSQPTYPGDDAPVRDLRRFYRDLRRYLNVVTRHRY
Physicochemical Analysis
C195H302N64O54
CEIKMW
R
4406.94
10.55
9
4
12
+4
9.06
-1.283
59.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5960
135.24
9
Residue Composition
number
1
A
8
R
1
N
4
D
0
C
0
E
1
Q
2
G
1
H
0
I
3
L
0
K
0
M
1
F
4
P
1
S
2
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 4 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 3 K: 0 M: 0 F: 1 P: 4 S: 1 T: 2 W: 0 Y: 4 V: 3
Chemical Descriptors
36
C195H302N64O54
4406.94
10.55
+4
9.06
-1.283
Free
L
Linear
Free
N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ai9 Tdtomato Npcs

Assay & Model

Ai9 or wild-type mice
Ai9 or wild-type mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
SpyCas9 RNPs
In vitro and in vivo
CCSCCCCSSSSCCCHHHHHHTHHHHSCHHHHTTSCC
Additional Detail Fields 1 fields
CCSCCCCSSSSCCCHHHHHHTHHHHSCHHHHTTSCC