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Peptide record

TPDB62206

HBD (DH3) Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB62206
HBD (DH3)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GPGLWERQAREHESECKAA
Physicochemical Analysis
C90H140N30O30S1
NDIMFTYV
E
2154.34
5.47
4
4
5
-1
9.67
-1.368
36.32
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
255.30
3
Residue Composition
number
3
A
2
R
0
N
0
D
1
C
4
E
1
Q
2
G
1
H
0
I
1
L
1
K
0
M
0
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 1 E: 4 Q: 1 G: 2 H: 1 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C90H140N30O30S1
2154.34
5.47
-1
9.67
-1.368
Free
L
Linear
Free
NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
EGFP protein
EGFP-HBD (DH3) could not be translocated into the cells.
In vitro
CCSCTTTTTTSCSSSCCC
Additional Detail Fields 1 fields
CCSCTTTTTTSCSSSCCC