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Peptide record

TPDB62205

435B peptide Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62205
435B peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with FITC
Sequence
GPFHFYQFLFPPV
Physicochemical Analysis
C84H106N16O16
ARNDCEIKMSTW
F
1595.86
7.77
1
0
7
+0
-3.05
0.462
52.31
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
93.37
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
1
H
0
I
1
L
0
K
0
M
4
F
3
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 0 L: 1 K: 0 M: 0 F: 4 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
13
C84H106N16O16
1595.86
7.77
+0
-3.05
0.462
Free
L
Linear
Conjugation with FITC
NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human carcinoma A431, HeLa and CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (FITC)
On A431 cells, similar to Tat but on HeLa and CHO
Caveolae-mediated and lipid raft-mediated endocytosis
In vitro
CCCCSCCSSCCC
Additional Detail Fields 1 fields
CCCCSCCSSCCC