Back to search

Peptide record

TPDB62181

CADY-2e (SEQ ID No: 12) Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62181
CADY-2e (SEQ ID No: 12)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Cysteamide group N-terminal: Acetylation
Sequence
Ac-GLWRALWRLLRSLWRLLWSQPKKKRKV
Physicochemical Analysis
C166H269N51O31
NDCEHIMFTY
L
3475.28
13.01
9
0
13
+9
-2.11
-0.600
115.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22000
633.04
3
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
7
L
4
K
0
M
0
F
1
P
2
S
0
T
4
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 7 K: 4 M: 0 F: 0 P: 1 S: 2 T: 0 W: 4 Y: 0 V: 1
Chemical Descriptors
27
C166H269N51O31
3475.28
13.01
+9
-2.11
-0.600
Cysteamide group
L
Linear
Acetylation
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa or HS-68 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7943581

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CTHHHHHHHHHHHTTCSSSTTCCCCCC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHTTCSSSTTCCCCCC