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Peptide record

TPDB62171

CADY-2 (SEQ ID No: 8) Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB62171
CADY-2 (SEQ ID No: 8)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Cysteamide group N-terminal: Acetylation
Sequence
Ac-GLWRALWRALWRSLWKLKWKV
Physicochemical Analysis
C137H206N38O23
NDCEQHIMFPTY
LW
2753.38
12.71
6
0
13
+6
-6.78
-0.195
116.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
27500
998.77
1
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
5
L
3
K
0
M
0
F
0
P
1
S
0
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 5 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 5 Y: 0 V: 1
Chemical Descriptors
21
C137H206N38O23
2753.38
12.71
+6
-6.78
-0.195
Cysteamide group
L
Linear
Acetylation
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa or HS-68 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7943581

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CTHHHHHHHTHHHHTTSCCCC
Additional Detail Fields 1 fields
CTHHHHHHHTHHHHTTSCCCC