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Peptide record

TPDB62158

sC18-Cys Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB62158
sC18-Cys
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLRKRLRKFRNKIKEKC-NH2
Physicochemical Analysis
C95H173N35O21S1
ADQHMPSTWYV
K
2173.70
12.01
9
1
4
+8
7.84
-1.618
68.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
4
R
1
N
0
D
1
C
1
E
0
Q
1
G
0
H
1
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C95H173N35O21S1
2173.70
12.01
+8
7.84
-1.618
Amidation
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Protein derived
Both CaaX-1(dis) and sC18-Cys(dis) internalized significantly stronger into cells compared with their reduced analogs
In vitro