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Peptide record

TPDB62137

[E7K]kB1 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB62137
[E7K]kB1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GLPVCGKTCVGGTCNTPGCTCSWPVCTRN
Physicochemical Analysis
C118H192N36O38S6
ADEQHIMFY
C
2915.40
8.02
2
0
5
+2
1.23
0.138
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
201.52
14
Residue Composition
number
0
A
1
R
2
N
0
D
6
C
0
E
0
Q
5
G
0
H
0
I
1
L
1
K
0
M
0
F
3
P
1
S
5
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 6 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 1 T: 5 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C118H192N36O38S6
2915.40
8.02
+2
1.23
0.138
Free
L
Hydrophobic
Linear
Free
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, Mm96L Or Hff-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Synthetic
E7K* have low internalization efficiency comparable with that of TAT-G*
In vitro
CCTTGGGGSCCCSSSSSCCGGGC
Additional Detail Fields 1 fields
CCTTGGGGSCCCSSSSSCCGGGC