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Peptide record

TPDB62136

DSPE-PEG-CPP (CPP-Lp) Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62136
DSPE-PEG-CPP (CPP-Lp)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and Peptipedia, with an available 3D structural model.
N-terminal: Lipid Peg derivativtive
Sequence
GLPRRRRRRRRR
Physicochemical Analysis
C67H131N39O13
ANDCEQHIKMFSTWYV
R
1691.03
13.30
9
0
1
+9
7.19
-3.225
32.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C67H131N39O13
1691.03
13.30
+9
7.19
-3.225
Free
L
Linear
Lipid Peg derivativtive
NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Murine brain microvascular endothelial cells (BMVECs)

Assay & Model

Male Sprague-Dawley (SD) rats
Male Sprague-Dawley (SD) rats

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nanoparticle (Liposomes)
In vitro and in vivo
CCTTCTTTCCCC
Additional Detail Fields 1 fields
CCTTCTTTCCCC