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Peptide record

TPDB62125

PN283 (SEQ ID NO: 73) Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB62125
PN283 (SEQ ID NO: 73)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLGSLLKKAGKKLKQPKSKRKV-NH2
Physicochemical Analysis
C108H202N34O26
NDCEHIMFTWY
K
2393.00
11.97
9
0
6
+9
7.71
-1.018
88.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
0
I
4
L
8
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 4 K: 8 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C108H202N34O26
2393.00
11.97
+9
7.71
-1.018
Amidation
L
Linear
Free
NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CGGGCTTSSCSSSSCCGGGSCC
Additional Detail Fields 1 fields
CGGGCTTSSCSSSSCCGGGSCC