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Peptide record

TPDB62124

Inv6 Cell-penetrating Peptides standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB62124
Inv6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 34-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
GLGDKFGESIVNANTVLDDLNSRMPQSRHDIQQL
Physicochemical Analysis
C159H259N49O55S1
CWY
DL
3769.16
4.54
4
5
11
-2
10.27
-0.629
88.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
10
Residue Composition
number
1
A
2
R
3
N
4
D
0
C
1
E
3
Q
3
G
1
H
2
I
4
L
1
K
1
M
1
F
1
P
3
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 3 D: 4 C: 0 E: 1 Q: 3 G: 3 H: 1 I: 2 L: 4 K: 1 M: 1 F: 1 P: 1 S: 3 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
34
C159H259N49O55S1
3769.16
4.54
-2
10.27
-0.629
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CTTTTTGGGTTCHHHHHHHHSSCCGGGCSSCCC
Additional Detail Fields 1 fields
CTTTTTGGGTTCHHHHHHHHSSCCGGGCSSCCC