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Peptide record

TPDB62120

ppTG Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB62120
ppTG
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker Di-Glycine
Sequence
GLFKALLKLLKSLWKLLLKAGGC
Physicochemical Analysis
C122H209N29O25S1
RNDEQHIMPTYV
L
2514.24
10.71
5
0
13
+5
-3.49
0.900
161.30
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
218.75
2
Residue Composition
number
2
A
0
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
0
I
9
L
5
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 9 K: 5 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
23
C122H209N29O25S1
2514.24
10.71
+5
-3.49
0.900
Free
Linker Di-Glycine
L
Linear
Free
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PNA
Endocytosis
In vitro
CTHHHHHHHHHHHHHHHTTTTCC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHHHHTTTTCC