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Peptide record

TPDB62116

HA2-penetratin Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB62116
HA2-penetratin
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLFGAIAGFIENGWEGMIDGRQIKIWFQNRRMKWKK-NH2
Physicochemical Analysis
C198H302N56O47S2
CHPSTYV
G
4283.04
10.95
7
3
16
+4
1.87
-0.461
70.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
385.24
4
Residue Composition
number
2
A
3
R
2
N
1
D
0
C
2
E
2
Q
6
G
0
H
5
I
1
L
4
K
2
M
3
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 1 C: 0 E: 2 Q: 2 G: 6 H: 0 I: 5 L: 1 K: 4 M: 2 F: 3 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
36
C198H302N56O47S2
4283.04
10.95
+4
1.87
-0.461
Amidation
L
Amphipathic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mges(Enzyme Solution Collected From The Midgut Of S.Gregaria) And S. Gregaria

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Cys fluorescently labelled dsRNA (dsTub and dsLuc) and siRNA( dsTub siRNA and dsLuc-siRNA)
In vitro and ex vivo
CTHHHHHHHHHHHHHHTC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHHHTC