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Peptide record

TPDB62114

HA2-TAT Cell-penetrating Peptides standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB62114
HA2-TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 33-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GLFGAIAGFIENGWEGLIEGWYGGRKKRRQRRR
Physicochemical Analysis
C173H269N57O43
DCHMPSTV
G
3835.39
11.77
8
3
12
+5
4.69
-0.858
65.15
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
325.65
3
Residue Composition
number
2
A
6
R
1
N
0
D
0
C
3
E
1
Q
8
G
0
H
3
I
2
L
2
K
0
M
2
F
0
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 0 C: 0 E: 3 Q: 1 G: 8 H: 0 I: 3 L: 2 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
33
C173H269N57O43
3835.39
11.77
+5
4.69
-0.858
Free
L
Amphipathic
Linear
Free
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mges(Enzyme Solution Collected From The Midgut Of S.Gregaria) And S. Gregaria

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Cys fluorescently labelled dsRNA (dsTub and dsLuc) and siRNA( dsTub siRNA and dsLuc-siRNA)
In vitro and ex vivo
CCCHHHHHHHSCCBTTBCCTTCSSCCSSCCCCCCCC
Additional Detail Fields 1 fields
CCCHHHHHHHSCCBTTBCCTTCSSCCSSCCCCCCCC