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Peptide record

TPDB62112

All-L Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB62112
All-L
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, and Peptipedia, with an available 3D structural model.
C-terminal: Biotinylation on Lysine
Sequence
GLFEAIEGFIENGWEGMIDGWYGGGGRRRRRRRRRK
Physicochemical Analysis
C187H293N67O49S1
CQHPSTV
RG
4295.86
11.87
10
5
11
+5
9.31
-1.264
46.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
290.74
2
Residue Composition
number
1
A
9
R
1
N
1
D
0
C
4
E
0
Q
9
G
0
H
3
I
1
L
1
K
1
M
2
F
0
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 9 N: 1 D: 1 C: 0 E: 4 Q: 0 G: 9 H: 0 I: 3 L: 1 K: 1 M: 1 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
36
C187H293N67O49S1
4295.86
11.87
+5
9.31
-1.264
Biotinylation on Lysine
L and D
Linear
Free
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Cal 27 Cancer Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L and D
Synthetic
CIP2A oncogene (DY547-siCIP2A)
Cytoplasm
In vitro
CCSHHHHTTTCSSSSCSSSSSSTTTTCTTGGGCCCC
Additional Detail Fields 1 fields
CCSHHHHTTTCSSSSCSSSSSSTTTTCTTGGGCCCC