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Peptide record

TPDB62110

HA2 Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB62110
HA2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GLFEAIEGFIENGWEGMIDGWYGAS
Physicochemical Analysis
C127H174N28O39S1
RCQHKPTV
G
2749.00
2.84
0
5
12
-5
0.96
0.044
70.40
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
454.35
3
Residue Composition
number
2
A
0
R
1
N
1
D
0
C
4
E
0
Q
6
G
0
H
3
I
1
L
0
K
1
M
2
F
0
P
1
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 0 E: 4 Q: 0 G: 6 H: 0 I: 3 L: 1 K: 0 M: 1 F: 2 P: 0 S: 1 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
25
C127H174N28O39S1
2749.00
2.84
-5
0.96
0.044
Free
L
Amphiphilic
Linear
Free
NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Protein derived
GFP-HiBiT fusion protein
Cytosol
Not significantly higher than GFP alone
Endocytosis
In vitro
CCCSSSSSCTTCTTTCCCCSSCCCSSCC
Additional Detail Fields 1 fields
CCCSSSSSCTTCTTTCCCCSSCCCSSCC