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Peptide record

TPDB62109

HA2TAT Cell-penetrating Peptides modified_plain modified
31 amino acids
Basic Information
3D PDB MODEL
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TPDB62109
HA2TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 31-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Modified, details unspecified
Sequence
GLFEAIEGFIEGGWEGMIDGYGRKKRRORRR
Physicochemical Analysis
C156H247N51O42S1
NCQHPSTV
G
3541.05
10.67
8
5
10
+3
9.28
-0.990
53.55
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
197.40
1
Residue Composition
number
1
A
6
R
0
N
1
D
0
C
4
E
0
Q
7
G
0
H
3
I
1
L
2
K
1
M
2
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 1 C: 0 E: 4 Q: 0 G: 7 H: 0 I: 3 L: 1 K: 2 M: 1 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
31
C156H247N51O42S1
3541.05
10.67
+3
9.28
-0.990
Free
Modified
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Assay & Model

Both male and female C57 BL/6J mice (aged: 7± 1 weeks average body weight: 20± 2 g)
Both male and female C57 BL/6J mice (aged: 7± 1 weeks average body weight: 20± 2 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Fusogenic
Brain-derived neurotrophic factor (BDNF)
In vitro and in vivo