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Peptide record

TPDB62105

MPG Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB62105
MPG
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GLAFLGFLGAAGSTMGAWSQPKKKRKV
Physicochemical Analysis
C129H208N36O32S1
NDCEHIY
G
2807.35
11.80
5
0
12
+5
-0.38
-0.004
68.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
195.91
4
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
1
Q
5
G
0
H
0
I
3
L
4
K
1
M
2
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 5 H: 0 I: 0 L: 3 K: 4 M: 1 F: 2 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C129H208N36O32S1
2807.35
11.80
+5
-0.38
-0.004
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Dc2.4 Dcs , Splenocytes From C57Bl/6 Mice

Assay & Model

C57BL/6 mice
C57BL/6 mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
FITC-dye and gp100 peptide to the N terminus
Cytosol
50-fold increase with Bpep in dendritic cells
Endocytosis
In vitro and in vivo
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC