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Peptide record

TPDB62104

Inv2 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB62104
Inv2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
GKYVSLTTPKNPTKRRITPKDV
Physicochemical Analysis
C111H191N33O32
ACEQHMFW
KT
2499.94
11.02
6
1
5
+5
7.61
-1.136
61.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
59.60
7
Residue Composition
number
0
A
2
R
1
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
4
K
0
M
0
F
3
P
1
S
4
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 4 M: 0 F: 0 P: 3 S: 1 T: 4 W: 0 Y: 1 V: 2
Chemical Descriptors
22
C111H191N33O32
2499.94
11.02
+5
7.61
-1.136
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCCCSTTSSBCSSSBCCCSCCC
Additional Detail Fields 1 fields
CCCCSTTSSBCSSSBCCCSCCC