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Peptide record

TPDB62101

P2 Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB62101
P2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Nonadecanoic acid (C19) on Lys
Sequence
GKRSAAAAAAK-NH2
Physicochemical Analysis
C41H76N16O13
NDCEQHILMFPTWYV
A
1001.15
11.64
3
0
6
+3
1.91
-0.245
54.55
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
6
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C41H76N16O13
1001.15
11.64
+3
1.91
-0.245
Amidation
Nonadecanoic acid (C19) on Lys
L
Amphiphilic
Linear
Free
NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Skbr3 Or MDA-MB-435 Cancer Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
Doxorubicin (Doxo)
Cytoplasm
In vitro
CCCCCCCGGGC
Additional Detail Fields 1 fields
CCCCCCCGGGC