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Peptide record

TPDB62094

TCF1-ALPHA Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB62094
TCF1-ALPHA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
GKKKKRKREKL-NH2
Physicochemical Analysis
C61H119N23O14
ANDCQHIMFPSTWYV
K
1398.76
11.72
8
1
1
+7
9.03
-2.955
35.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
1
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C61H119N23O14
1398.76
11.72
+7
9.03
-2.955
Amidation
L
Cationic
Linear
Conjugation with fluorescein
NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
50% relative to Oct-6
Energy independent, non-receptor-mediated process
In vitro
CCCCCSTTCCC
Additional Detail Fields 1 fields
CCCCCSTTCCC