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Peptide record

TPDB62089

Peptide1 or Pep-1 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB62089
Peptide1 or Pep-1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with CF
Sequence
GKETWWETWWTEWSQPKKKRKV-NH2
Physicochemical Analysis
C138H198N36O34
ANDCHILMFY
KW
2905.31
10.38
6
3
6
+3
4.23
-1.964
13.18
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
27500
946.54
5
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
3
E
1
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
1
P
1
S
3
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 3 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 1 S: 1 T: 3 W: 5 Y: 0 V: 1
Chemical Descriptors
22
C138H198N36O34
2905.31
10.38
+3
4.23
-1.964
Amidation
L
Amphiphilic
Linear
Conjugated with CF
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Hek293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Amphiphilic
Chimeric
(5(6)-CF) dye
Endosomes and Lysosomes
Endocytosis
In vitro