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Peptide record

TPDB62076

Pep-1_R Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB62076
Pep-1_R
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIRRFLRSARRFVRAFR-NH2
Physicochemical Analysis
C97H162N38O19
NDCEQHKMPTWY
R
2164.60
13.18
7
0
8
+7
1.28
-0.482
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
7
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
0
K
0
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C97H162N38O19
2164.60
13.18
+7
1.28
-0.482
Amidation
L
Amphipathic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Huh-7-Luc Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Amphipathic
Synthetic
Cy5-plasmid DNA , mRNA , siRNA
Cytoplasm
Pep-1_R did not show increased luminescence than Pep-1
In vitro