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Peptide record

TPDB62063

MG2A Cell-penetrating Peptides standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB62063
MG2A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 42-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
Sequence
GIGKFLHSAKKFGKAFVGEIMNSGGKKWKMRRNQFWVKVQRG
Physicochemical Analysis
C222H351N67O51S2
DCPTY
K
4838.77
12.20
12
1
16
+10
5.67
-0.657
53.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
227.33
6
Residue Composition
number
2
A
3
R
2
N
0
D
0
C
1
E
2
Q
7
G
1
H
2
I
1
L
8
K
2
M
4
F
0
P
2
S
0
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 0 C: 0 E: 1 Q: 2 G: 7 H: 1 I: 2 L: 1 K: 8 M: 2 F: 4 P: 0 S: 2 T: 0 W: 2 Y: 0 V: 3
Chemical Descriptors
42
C222H351N67O51S2
4838.77
12.20
+10
5.67
-0.657
Free
L
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa and A549 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Peptide (Antmicrobial peptide MG2)
In vitro
CCSTTCSHHHHSCCSTTHHHHSSCSCCSCCSSCSCCCCCCC
Additional Detail Fields 1 fields
CCSTTCSHHHHSCCSTTHHHHSSCSCCSCCSSCSCCCCCCC