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Peptide record

TPDB62062

pHD118 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62062
pHD118
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GIGEVLHELADDLPELQSWIKAAQQL
Physicochemical Analysis
C129H205N33O41
RNCMFTY
L
2874.24
3.92
2
5
12
-4
7.10
-0.062
127.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
191.35
4
Residue Composition
number
3
A
0
R
0
N
2
D
0
C
3
E
3
Q
2
G
1
H
2
I
5
L
1
K
0
M
0
F
1
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 2 C: 0 E: 3 Q: 3 G: 2 H: 1 I: 2 L: 5 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C129H205N33O41
2874.24
3.92
-4
7.10
-0.062
Free
L
Amphiphilic
Linear
Free
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Protein derived
GFP-HiBiT fusion protein
Cytosol
Not significantly higher than GFP alone
Endocytosis
In vitro
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC