Back to search

Peptide record

TPDB62061

AAM Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62061
AAM
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIGAVLHVLTTGLPALISWIHHHHQQ-NH2
Physicochemical Analysis
C131H203N39O32
RNDCEKMFY
H
2836.29
8.20
5
0
12
+0
1.63
0.454
135.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
193.91
5
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
2
Q
3
G
5
H
3
I
4
L
0
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 5 I: 3 L: 4 K: 0 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C131H203N39O32
2836.29
8.20
+0
1.63
0.454
Amidation
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16-F10 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
FITC-conjugated
FITC-AAM at pH 5.5 showed approximately two-fold high cell-penetrating activity compared with pH 7.4
In vitro