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Peptide record

TPDB62058

Mel-L9L13 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62058
Mel-L9L13
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GIGAILKVEATGEPTLISWIKNKRKQ
Physicochemical Analysis
C129H220N36O36
DCHMFY
IK
2851.39
10.55
5
2
10
+3
6.22
-0.254
108.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
192.89
5
Residue Composition
number
2
A
1
R
1
N
0
D
0
C
2
E
1
Q
3
G
0
H
4
I
2
L
4
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 3 H: 0 I: 4 L: 2 K: 4 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C129H220N36O36
2851.39
10.55
+3
6.22
-0.254
Free
L
Cationic
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Alexa488-dextran
Endosomes
In vitro
CCCGGGTTTTTCCSSHHHHHHTTCCC
Additional Detail Fields 1 fields
CCCGGGTTTTTCCSSHHHHHHTTCCC