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Peptide record

TPDB62057

Mel-V8G12 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62057
Mel-V8G12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GIGAILKELATELPTLISWIKNKRKQ
Physicochemical Analysis
C134H230N36O36
DCHMFYV
ILK
2921.52
10.55
5
2
11
+3
5.02
-0.108
127.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
188.26
5
Residue Composition
number
2
A
1
R
1
N
0
D
0
C
2
E
1
Q
2
G
0
H
4
I
4
L
4
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 2 H: 0 I: 4 L: 4 K: 4 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
26
C134H230N36O36
2921.52
10.55
+3
5.02
-0.108
Free
L
Cationic
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Alexa488-dextran
Cytosol
In vitro
CCSSTTHHHHTTSTTHHHHHHTTCCC
Additional Detail Fields 1 fields
CCSSTTHHHHTTSTTHHHHHHTTCCC