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Peptide record

TPDB62041

secR8 Cell-penetrating Peptides modified_plain modified
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62041
secR8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 16-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: B =β-alanine, GG linker
Sequence
GGRXRRXRRXRRXRXB-NH2
Physicochemical Analysis
C52H104N34O11
ANDCEQHILKMFPSTWYV
R
1381.62
13.25
8
0
0
+8
6.50
-2.300
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C52H104N34O11
1381.62
13.25
+8
6.50
-2.300
Amidation
B =β-alanine, GG linker
Modified
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs, U937 Macrophages

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Synthetic
FAM-labelled anti-miR-155 PNA
The percentage of labelled cells for the SecR8 was only 32% at 200nM
In vitro