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Peptide record

TPDB62032

TAT Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62032
TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GGRKKRRQRRRPPQAS
Physicochemical Analysis
C78H144N38O20
NDCEHILMFTWYV
R
1934.24
13.10
8
0
1
+8
8.88
-2.800
6.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C78H144N38O20
1934.24
13.10
+8
8.88
-2.800
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
GFP-HiBiT fusion protein
Cytosol
Significantly enhanced delivery (7- to 30-fold increase)
Endocytosis
In vitro
CBTTBC
Additional Detail Fields 1 fields
CBTTBC