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Peptide record

TPDB62030

Cell-penetrating Peptides standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB62030
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 39-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GGPSQPTYPGDDAPVRDLIRFYRDLRRYLNVVTRHRYAS
Physicochemical Analysis
C203H314N64O58
CEKMW
R
4579.12
10.16
8
4
14
+3
7.91
-0.938
67.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5960
130.16
10
Residue Composition
number
2
A
7
R
1
N
4
D
0
C
0
E
1
Q
3
G
1
H
1
I
3
L
0
K
0
M
1
F
4
P
2
S
2
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 2 R: 7 N: 1 D: 4 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 3 K: 0 M: 0 F: 1 P: 4 S: 2 T: 2 W: 0 Y: 4 V: 3
Chemical Descriptors
39
C203H314N64O58
4579.12
10.16
+3
7.91
-0.938
Free
L
Cationic
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
GFP-HiBiT fusion protein
Cytosol
Not significantly higher than GFP alone
Endocytosis
In vitro
CCSSCSSCC
Additional Detail Fields 1 fields
CCSSCSSCC