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Peptide record

TPDB62019

R8 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62019
R8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: PMO Ivs2-654 Attached
Sequence
GGKGGRRRRRRRR
Physicochemical Analysis
C62H122N38O14
ANDCEQHILMFPSTWYV
R
1623.90
13.25
9
0
0
+9
7.51
-3.192
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C62H122N38O14
1623.90
13.25
+9
7.51
-3.192
Free
L
Cationic
Linear
PMO Ivs2-654 Attached
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654 And C2C12 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Synthetic
PMO IVS2-654-Biotin
Cytoplasm
L and D-peptides shared nearly identical PMO delivery activities
Endocytosis
In vitro